Dorothy Bishop describes how threats to reproducibility, recognized but unaddressed for decades, might finally be brought under control.

Opportunities for moving between academia and business are expanding for scientists as companies step up recruitment.

Facing a big data challenge? Seek the skills of a research software engineer (or become one yourself)

A tunable interlayer twist that evolves naturally during synthesis of van der Waals nanowires made from layered crystals of germanium sulfide could produce new electronic structure and correlation phenomena.

The advent of sex-selective abortion has ushered in changes in the sex ratio of newborns.

Networking is a crucial skill for all scientists. Ruth Gotian offers tips for those who struggle to make it work.

Entombed by debris nearly 40 years ago, a river in the northwestern United States runs again.

Immune responses in the gut and associated draining lymph nodes differ between tolerogenic and inflammatory depending on their anatomical location.

Lightning observed with unprecedented spatial resolution.

Hear the biggest stories from the world of science | 18 April 2019

Micro-computed tomography and magnetic resonance imaging of a growth series of the coelacanth Latimeria chalumnae traces the ontogeny of the brain and neurocranium, which sheds light on neurocranial evolution in sarcopterygian fishes.

The restoration of some structures and cellular functions in pig brains hours after death could intensify debates about when human organs should be removed for transplantation, warn Stuart Youngner…

A spongy form of graphene can also maintain its resilience when subjected to extreme heat.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Researchers need guidance on animal use and the many issues opened up by a new study on whole-brain restoration, argue Nita A. Farahany, Henry T. Greely and Charles M. Giattino.

Observation of an exotic polarization pattern.

Stellar baby boom added a slew of stars to the Galaxy’s disk.

Identification of the changes that converted a transposase to a recombinase sheds light on the evolution of the vertebrate adaptive immune system.

This Review discusses particle injection pumps, which inject suspended and sinking particles to different ocean depths and may sequester as much carbon as the biological gravitational pump.

All those in the research enterprise must support efforts to conduct just, equitable and inclusive research.

Structures made of DNA are designed to target the bacteria that cause cholera.

Studies of the planetary nebula NGC 7027, using an upgraded spectrometer onboard a high-altitude observatory, have identified the rotational ground-state transition of the helium hydride ion—the first molecule to form after the Big Bang and an essential precursor to molecular hydrogen.

DNA analysis helps to resolve two cases of mistaken identity among Madagascan stick insects.

Thousands of Nature referees have chosen to be publicly acknowledged.