9 Best Articles in 2022
MIT Technology Review
EXCLUSIVE: Chinese scientists are creating CRISPR babies
MIT Technology Review
10 min read · From 2018 · A daring effort is under way to create the first children whose DNA has been tailored using gene editing.
Reader View · Shared by 188, including Dominik Grolimund, grimm, Korben, Kim Dik, Ste Davies, Nils Hitze, Ryan Hoover, Tom Connor, Wesley Fryer, Ph.D. 🌎🎙🚀 (he/him), Ⓓarío Macchi, Benedict Evans, Florian Hanke 🍎, Sascha Brossmann (he/him) 🇪🇺🇺🇦, Luca Like, Gerd Leonhard, Andreia Costa 🇵🇹, Tom+ ✈️ Consensus Austin, Ian King, Balaji Srinivasan, Azeem Azhar
Singularity Hub
Scientists Used CRISPR to Engineer a New 'Superbug' That's Invincible to All Viruses
Singularity Hub
5 min read · 2021-06-09 · The team used CRISPR to replace over 18,000 codons with synthetic amino acids that don’t exist anywhere in the natural world.
Reader View · Shared by 102, including John Hagel, Brian Laung Aoaeh, CFA, Brian Ahier, Howard Getson, Matthew Turland
MIT Technology Review
EXCLUSIVE: First human embryos edited in U.S., using CRISPR
MIT Technology Review
6 min read · From 2017 · Researchers have demonstrated they can efficiently improve the DNA of human embryos.
Reader View · Shared by 94, including Will Hoekenga, Nils Hitze, Alain, Liv 😷, Richard MacManus, Tauno, Alex Barrera, Thomas Power, Florian Hanke 🍎, Jakub Albert Ferenc, Claudia Sommer
The Atlantic
The CRISPR Baby Scandal Gets Worse by the Day
The Atlantic
~13 min read · From 2018 · The alleged creation of the world's first gene-edited infants was full of technical errors and ethical blunders. Here are the 15 most damning details.
Reader View · Shared by 81, including George M 🇪🇺, Dominik Grolimund, Charles Baldwin, Luca Like, Merkstatt, Gerd Leonhard, Alex Barrera, Chris Messina, Jelan Ong, Josep M. Ganyet
NPR
CRISPR Scientist's Biography Explores Ethics Of Rewriting The Code Of Life
NPR
5 min read · 2021-03-08 · The Code Breaker profiles Jennifer Doudna, a Nobel Prize-winning biochemist key to the development of CRISPR, and examines the technology's exciting possibilities and need for oversight.
Reader View · Shared by 60
Fast Company
These are the 5 most dystopian technologies of 2020 and beyond
Fast Company
7 min read · From 2019 · From CRISPR to deepfakes, these are the technologies that could cause calamity in the future.
Reader View · Shared by 267, including Klaus Eck, Jennifer Stirrup - Next: #WWDVC #AI #Data #keynote, Evan Kirstel the $B2B Techfluencer, Katja Evertz, Ines Bieler, Matthias Lampe, Gabriele, Stephan Woodtli, Mark Tabladillo PhD, Theodora (Theo) Lau - 劉䂀曼 🌻, Mario Clemente, Faik Ersoy, LARRY ELKAN
CNET
Using CRISPR to resurrect the woolly mammoth
CNET
~16 min read · From 2019 · De-extinction, bringing extinct species back from the dead, is now on the table thanks to the revolutionary gene-editing technology CRISPR.
Reader View · Shared by 24, including Marsha Collier, Mathew Ingram
youtube.com
Genetic Engineering Will Change Everything Forever
youtube.com
From 2016 · Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming rea...
Shared by 54, including Max Roser, Nettra Pan 🦇🔊, Mark Pitman, Marco Unternaehrer, ̗̀ ̗̀Manuel Marquina, Edney Souza 🧙♂️, ThomNagy, Gui Schmitt
CB Insights
What Is CRISPR?
CB Insights
~20 min read · From 2018 · CRISPR. What is it? And why is the scientific community so fascinated by its potential applications? Starting with its definition, we explain how this technology harnesses an ancient bacteria-based…
Reader View · Shared by 17, including Vikram Dutt
Trending
Singularity Hub
A One-and-Done CRISPR Gene Therapy Will Aim to Prevent Heart Attacks
Singularity Hub
5 min read · May 17th · Scientists know the DNA letter swap that can, in theory, drastically lower LDL-C and in turn throttle the risk of heart attacks.
newswise.com
CRISPR Clinical Trials: A 2022 Update
newswise.com
~13 min read · Apr 1st · A comprehensive look at all of the active clinical trials on new CRISPR-based genome editing therapies in 2022, and perspective on what is coming next.
Reader View · Shared by 6, including Berci Meskó, MD, PhD, Evan Kirstel the $B2B Techfluencer
nature
Boosting plant genome editing with a versatile CRISPR-Combo system
nature
7 min read · May 23rd · Pan et al. develop a versatile CRISPR-Combo platform for simultaneous genome editing (targeted mutagenesis or base editing) and gene activation in plants, representing a versatile genome engineering…
Reader View · Shared by 6, including Botany One
STAT
In the wake of big patent decision, it’s business as usual for CRISPR therapy developers
STAT
3 min read · Mar 31st · Companies that are actually turning CRISPR into medicines are plowing through the fallout of the recent patent decision with little more than a collective shrug.
Reader View · Shared by 6, including Matthew Herper
More like this
news.berkeley.edu
FDA approves first test of CRISPR to correct genetic defect causing sickle cell disease
news.berkeley.edu
7 min read · 2021-03-30 · UC scientists and physicians hope to permanently cure patients of sickle cell disease by using CRISPR-Cas9 to replace a defective gene with the normal version
Reader View · Shared by 29, including Martin Varsavsky 🇺🇦, Carl Zimmer
Y Combinator
Hacking DNA: The Story of CRISPR, Ken Thompson, and the Gene Drive
Y Combinator
10 min read · From 2017 · Before CRISPR, genetic engineering was slow, expensive, and inaccurate. With CRISPR, genome editing is cheap, accurate, and repeatable. This is the story of CRISPR, concluding with a discussion of Gene Drive, a biological technique which, when used with CRISPR, gives even greater power to genetic en
Reader View · Shared by 29, including Howard Getson, Charles Kubicek, Ha Duong
Scientific American
Mail-Order CRISPR Kits Allow Absolutely Anyone to Hack DNA
Scientific American
~16 min read · From 2017 · Experts debate what amateur scientists could accomplish with the powerful DNA editing tool—and whether its ready availability is cause for concern
Reader View · Shared by 36, including Nils Hitze, Gerd Leonhard, Bjorn Larsen, Howard Getson, Noah Smith 🐇🇺🇦
STAT
Two female CRISPR scientists make history, winning Nobel in chemistry
STAT
5 min read · 2020-10-07 · Emmanuelle Charpentier of the Max Planck Institute and Jennifer Doudna of the University of California have won for their CRISPR discovery.
Reader View · Shared by 31, including Helen Branswell 🇺🇦, Yvette d’Entremont, SusanaDeLeón, MD, Amesh Adalja, Skoll Foundation, Matthew Herper, Sharmila Dissanaike, Jeffrey Flier, John Schwartz
nature
CRISPR Gene Editing in Human Embryos Wreaks Chromosome Mayhem
nature
4 min read · 2020-06-25 · Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing
Reader View · Shared by 134, including Howard Getson, Roger Highfield, Wesley Fryer, Ph.D. 🌎🎙🚀 (he/him), Eric Topol
MIT Technology Review
CRISPR in 2018: Coming to a Human Near You
MIT Technology Review
3 min read · From 2017 · The first clinical trials are slated to begin in the U.S. and Europe while others are stalled.
Reader View · Shared by 37, including Tom Connor, Merkstatt, Gerd Leonhard
Science Magazine
CRISPR injected into the blood treats a genetic disease for first time
Science Magazine
3 min read · 2021-06-26 · Novel treatment using messenger RNA sharply cuts production of mutant liver protein, although it’s too early to show patients with rare condition benefit
Reader View · Shared by 131, including Howard Getson, Grzegorz Wapiński, Berci Meskó, MD, PhD, Evan Kirstel the $B2B Techfluencer, Brian D. Earp, Ph.D., Eric Topol, Jeffrey Flier, News from Science, Roger Highfield
Singularity Hub
CRISPR On-Off Switch Will Help Unlock the Secrets of Our Immune System
Singularity Hub
5 min read · Mar 8th · Though previously used in immortal cells grown in labs, this is the first time these CRISPR tools are rejiggered for cells from our bodies.
MIT Technology Review
China’s CRISPR twins might have had their brains inadvertently enhanced
MIT Technology Review
4 min read · From 2019 · New research suggests that a controversial gene-editing experiment to make children resistant to HIV may also have enhanced their ability to learn and form memories.
Reader View · Shared by 116, including Merkstatt, jason@calacanis.com, ashley r 🇺🇦 🇺🇦, 🟣 Antonio Vieira Santos #FutureOfWork, Yvette Dubel, Vikram Dutt, Bryan Onel, Jose Luis Calvo, Paul Graham, Nico Müller 🇺🇦, Marsha Collier
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