9 Best Articles in 2022
CB Insights
What Is CRISPR?
CB Insights
~20 min read · From 2018 · CRISPR. What is it? And why is the scientific community so fascinated by its potential applications? Starting with its definition, we explain how this technology harnesses an ancient bacteria-based… · Shared by 90, including Vikram Dutt
MIT Technology Review
EXCLUSIVE: Chinese scientists are creating CRISPR babies
MIT Technology Review
10 min read · From 2018 · A daring effort is under way to create the first children whose DNA has been tailored using gene editing. · Shared by 187, including Ste Davies, grimm, Korben, Kim Dik, Dominik Grolimund, Nils Hitze, Ryan Hoover, Tom Connor, Wesley Fryer, Ph.D. 🌎🎙🚀 (he/him), Ⓓarío Macchi, Benedict Evans, Florian Hanke 🍎, Sascha Brossmann (he/him) 🇪🇺🇺🇦, Luca Like, Gerd Leonhard, Andreia Costa 🇵🇹, Tom Howard ✈️ NYC, Ian King, Balaji Srinivasan, Azeem Azhar
Singularity Hub
Scientists Used CRISPR to Engineer a New 'Superbug' That's Invincible to All Viruses
Singularity Hub
5 min read · 2021-06-09 · The team used CRISPR to replace over 18,000 codons with synthetic amino acids that don’t exist anywhere in the natural world. · Shared by 102, including John Hagel, Brian Laung Aoaeh, CFA, Brian Ahier, Howard Getson, Matthew Turland
MIT Technology Review
EXCLUSIVE: First human embryos edited in U.S., using CRISPR
MIT Technology Review
6 min read · From 2017 · Researchers have demonstrated they can efficiently improve the DNA of human embryos. · Shared by 93, including Will Hoekenga, Nils Hitze, Jakub Ferenc, Liv 😷, Richard MacManus, Tauno, Alex Barrera, Thomas Power, Florian Hanke 🍎, Alain, Claudia Sommer
nature
A CRISPR view of gene function
nature
6 min read · Jun 9th · Next-generation sequencing methods that provide multi-omic read-outs of CRISPR-modified cells reveal the relevance of genetic variants to disease states. · Shared by 64
NPR
CRISPR Scientist's Biography Explores Ethics Of Rewriting The Code Of Life
NPR
5 min read · 2021-03-08 · The Code Breaker profiles Jennifer Doudna, a Nobel Prize-winning biochemist key to the development of CRISPR, and examines the technology's exciting possibilities and need for oversight. · Shared by 60
Singularity Hub
New CRISPR Tool Protects Against Viruses Without Making Any DNA Cuts
Singularity Hub
5 min read · Jun 7th · The study shows that chopping up viral DNA isn’t the only route for antiviral defense, at least in bacteria cells. · Shared by 83, including Brian Ahier, John Hagel
The New York Times
Her Discovery Changed the World. How Does She Think We Should Use It?
The New York Times
8 min read · Aug 15th · “It’s a little scary, quite honestly,” says Dr. Jennifer Doudna, who helped develop CRISPR gene-editing technology. · Shared by 74, including Matthew Herper
The Atlantic
The CRISPR Baby Scandal Gets Worse by the Day
The Atlantic
~13 min read · From 2018 · The alleged creation of the world's first gene-edited infants was full of technical errors and ethical blunders. Here are the 15 most damning details. · Shared by 81, including George M 🇪🇺, Dominik Grolimund, Charles Baldwin, Luca Like, Merkstatt, Gerd Leonhard, Alex Barrera, Chris Messina, Jelan Ong, Josep M. Ganyet
Trending
The New York Times
Her Discovery Changed the World. How Does She Think We Should Use It?
The New York Times
8 min read · Aug 15th · “It’s a little scary, quite honestly,” says Dr. Jennifer Doudna, who helped develop CRISPR gene-editing technology. · Shared by 74, including Matthew Herper
WIRED
There’s New Proof Crispr Can Edit Genes Inside Human Bodies
WIRED
2 min read · Sep 22nd · The technique had largely been limited to editing patients’ cells in the lab. New research shows promise for treating diseases more directly. · Shared by 54, including Berci Meskó, MD, PhD, Daniel Kraft, MD
The Wall Street Journal
Crispr Gene-Editing Drugs Show Promise in Preliminary Study
The Wall Street Journal
1 min read · Sep 16th · Intellia Therapeutics said two of its experimental Crispr treatments produced positive results in early-stage trials. · Shared by 11, including Evan Kirstel the $B2B Techfluencer
STAT
Intellia says CRISPR treatment safely corrects DNA of six patients with rare disease
STAT
1 min read · Sep 16th · Intellia Therapeutics said Friday the first six patients to receive its CRISPR-based treatment for a genetic swelling disorder have safely had small, corrective changes made to dysfunctional DNA… · Shared by 11, including Matthew Herper, Eric Topol
More like this
The Atlantic
The CRISPR Baby Scandal Gets Worse by the Day
The Atlantic
~13 min read · From 2018 · The alleged creation of the world's first gene-edited infants was full of technical errors and ethical blunders. Here are the 15 most damning details. · Shared by 81, including George M 🇪🇺, Dominik Grolimund, Charles Baldwin, Luca Like, Merkstatt, Gerd Leonhard, Alex Barrera, Chris Messina, Jelan Ong, Josep M. Ganyet
CNET
Using CRISPR to resurrect the woolly mammoth
CNET
~16 min read · From 2019 · De-extinction, bringing extinct species back from the dead, is now on the table thanks to the revolutionary gene-editing technology CRISPR. · Shared by 24, including Marsha Collier, Mathew Ingram
The New York Times
CRISPR, 10 Years On: Learning to Rewrite the Code of Life
The New York Times
~12 min read · Jun 27th · The gene-editing technology has led to innovations in medicine, evolution and agriculture — and raised profound ethical questions about altering human DNA. · Shared by 218, including Bernardo van Olst, Forbes India, Carl Zimmer, Eric Topol, Packy McCormick, Daniel Kraft, MD, Michael (मुकेश) 🇺🇦💪🏻
news.berkeley.edu
FDA approves first test of CRISPR to correct genetic defect causing sickle cell disease
news.berkeley.edu
7 min read · 2021-03-30 · UC scientists and physicians hope to permanently cure patients of sickle cell disease by using CRISPR-Cas9 to replace a defective gene with the normal version · Shared by 29, including Martin Varsavsky 🇺🇦, Carl Zimmer
Y Combinator
Hacking DNA: The Story of CRISPR, Ken Thompson, and the Gene Drive
Y Combinator
10 min read · From 2017 · Before CRISPR, genetic engineering was slow, expensive, and inaccurate. With CRISPR, genome editing is cheap, accurate, and repeatable. This is the story of CRISPR, concluding with a discussion of Gene Drive, a biological technique which, when used with CRISPR, gives even greater power to genetic en · Shared by 29, including Howard Getson, Charles Kubicek, Ha Duong
youtube.com
Genetic Engineering Will Change Everything Forever
youtube.com
From 2016 · Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming rea... · Shared by 54, including Max Roser, Dr. Nettra Pan 🦇🔊, Mark Pitman, Marco Unternaehrer, ̗̀ ̗̀Manuel Marquina, Edney Souza 🧙♂️, ThomNagy, Gui Schmitt
Scientific American
Mail-Order CRISPR Kits Allow Absolutely Anyone to Hack DNA
Scientific American
~16 min read · From 2017 · Experts debate what amateur scientists could accomplish with the powerful DNA editing tool—and whether its ready availability is cause for concern · Shared by 36, including Nils Hitze, Gerd Leonhard, Bjorn Larsen, Howard Getson, Noah Smith 🐇🇺🇦
STAT
Two female CRISPR scientists make history, winning Nobel in chemistry
STAT
5 min read · 2020-10-07 · Emmanuelle Charpentier of the Max Planck Institute and Jennifer Doudna of the University of California have won for their CRISPR discovery. · Shared by 31, including Helen Branswell 🇺🇦, Yvette d’Entremont, SusanaDeLeón, MD, Amesh Adalja, Skoll Foundation, Matthew Herper, Sharmila Dissanaike, Jeffrey Flier, John Schwartz
nature
CRISPR Gene Editing in Human Embryos Wreaks Chromosome Mayhem
nature
4 min read · From 2020 · Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing · Shared by 134, including Howard Getson, Roger Highfield, Wesley Fryer, Ph.D. 🌎🎙🚀 (he/him), Eric Topol
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