The Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network of the National Heart, Lung, and Blood Institute conducted the Reevaluation of Systemic Early Neuromuscular…

By 2040, deaths from chronic hepatitis are projected to exceed the combined mortality associated with HIV infection, tuberculosis, and malaria. Recognizing both the advances that have been made and…

Original Article Neuromuscular Blockade for ARDS The National Heart, Lung, and Blood Institute PETAL Clinical Trials Network This trial revisited research conducted about a decade ago that showed a…

A recent multicenter study examined the causes of severe acute liver injury in patients with an aspartate aminotransferase or alanine aminotransferase level of more than 1000 U per liter and confirmed…

It is estimated that 1.5 million patients receive cardiac implantable electronic devices (CIEDs) worldwide every year. Tarakji et al. conducted a randomized, controlled, postmarketing, interventional…

I recently saw a patient for follow-up who had a history of atrial fibrillation and was taking apixaban for cardioembolic risk reduction. The patient was treated in the emergency department for acute…

Clinical training is a priority during medical school and residency, but trainees shouldn’t put the rest of their lives on hold. How can you maximize your efficiency in and out of the hospital to live…

In recent years, numerous cases of chronic kidney disease have emerged among agricultural workers, as well as among others performing manual labor, in various regions of the world. The disease does…

Miscarriage affects one in five pregnancies. Coomarasamy et al. conducted a multicenter, randomized, double-blind, placebo-controlled trial to evaluate whether treatment with progesterone during the…

Jay is a 14-year-old boy who comes with his dad to your primary care office for a follow-up to a school evaluation for attention deficit–hyperactivity disorder (ADHD). He has been struggling in school…

Myotonic dystrophy is a group of nucleotide repeat expansion diseases that are characterized by hyperexcitable muscle with impaired relaxation (myotonia). Read the Clinical Problem-Solving article…

Hypoparathyroidism is suspected in patients with a low ionized or albumin-corrected blood calcium level, hyperphosphatemia, and an intact PTH level that is low or that is inappropriately in the normal…

Mr. Sampson, a 67-year-old man, was making coffee in his kitchen when he suddenly collapsed and became unresponsive. His wife was present and called 911. Mr. Sampson has a known history of coronary…

Whether it’s internal medicine, primary care, endocrinology, emergency medicine or surgery, womens’ health questions present themselves in a range of specialties far beyond OBGYN. When should HRT be…

A shortage of available donor hearts and lungs limits transplantation in the United States, where approximately 1000 patients die each year while waiting for these organs. Woolley et al. conducted an…

Hazardous chemical emergencies and related poisonings result from various exposures, including inadvertent residential, industrial, occupational, or transportation mishaps; natural disasters; and…

Mr. Watt is a 65-year-old man who was admitted to the medical intensive care unit for acute respiratory distress syndrome caused by bacterial pneumonia. He is currently on vasopressors and intubated…

In the presence of structural heart disease, ventricular tachycardia is typically monomorphic and is usually due to a reentrant mechanism resulting from the formation of an abnormal electrical circuit…

Signs of lower motor neuron dysfunction include muscle cramps, atrophy, and fasciculations. Spasticity and hyperreflexia are the most readily identifiable signs of upper motor neuron disease. Read the…

The rare disorder disables the immune system

The moment has finally arrived…it’s time to put on your short white coat, head to the wards, immerse yourself in the world of clinical medicine, and learn how to take care of patients. Far away from…